甲硝基羟乙唑(Metronidazolum)为中国药典(1977年版)法定名称,国内商品名灭滴灵,又称甲硝哒唑,国外商品名Flagyl。在化学上属咪唑类衍生物。结构式为: 二十多年来它一直作为抗滴虫和抗阿米巴药物应用于临床。自1972年Tally等首次报告用本品治疗全身性厌氧杆菌感染获得良好效果后方引起临床的重视。近十几年来研究证明:本品对厌氧菌有很强的抗菌或杀菌活性,临床效果明显,为此,从1978年起已被世界卫生组织遴选为抗厌氧菌感染的基本药物。最 Metronidazole (Metronidazolum) Chinese Pharmacopoeia (1977 edition) the legal name, the domestic trade name metronidazole, also known as metronidazole, foreign trade name Flagyl. Chemically, imidazole derivatives. The structural formula is: It has been used clinically as anti-trichomonad and anti-amoebic drug for more than two decades. Since 1972, Tally and other first reported with this product for the treatment of systemic anaerobic bacilli infection received good results behind the clinical attention. Nearly a decade of research shows that: This product has a strong antibacterial or bactericidal activity against anaerobic bacteria, clinical effect is obvious, for which, since 1978, has been selected by the World Health Organization as an anti-anaerobic bacterial infection of essential drugs. most