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目的观察卡前列素氨丁三醇预防剖宫产术后出血的临床效果。方法有产科剖宫产的指征而宫缩乏力高危因素者孕妇84例按照随机分配原则,分为观察组和对照组各42例,对照组剖宫产术常规操作,在胎儿娩出后,立即宫体肌内注射缩宫素20u,同时静脉滴注缩宫素20u;观察组在对照组的基础上同时宫体注射卡前列素氨丁三醇250μg。结果观察组产后2h内出血量(147.67±28.67)mL、2~24h出血量(367.34±45.56)mL、产后出血发生率4.76%,均低于对照组的(223.56±37.78)mL(、435.34±57.23)mL、19.04%(P<0.05);不良反应轻微,治疗结束后可恢复。结论对于有产后出血高危因素的患者,卡前列素氨丁三醇预防产后出血具有显著效果。
Objective To observe the clinical effect of carboprost trometamol in preventing bleeding after cesarean section. Methods Eighty-eight pregnant women with indications for cesarean section and high risk factors for uterine inertia were divided into observation group and control group with 42 cases in each group. The control group received routine operation of cesarean section immediately after the delivery of the fetus Intrauterine intramuscular injection of oxytocin 20u, while intravenous infusion of oxytocin 20u; observation group in the control group based on the same time, the body injected carboprost tromethamine 250μg. Results The amount of hemorrhage (147.67 ± 28.67) mL, the amount of hemorrhage after 2 ~ 24h (367.34 ± 45.56) mL and the rate of postpartum hemorrhage in observation group within 2h postpartum were all lower than those in the control group (223.56 ± 37.78 mL, 435.34 ± 57.23 ) mL, 19.04% (P <0.05). Adverse reactions were mild and recovered after treatment. Conclusion For patients with high risk of postpartum hemorrhage, carboprost trometamol has a significant effect in preventing postpartum hemorrhage.