纤维蛋白原（Ｆｑ）基因ＴａｑⅠ限制性内切酶位点的多态性与儿童单纯性肥胖及最大有氧能力关联，Ｔ１纯合子肥胖的健康风险较高，心肺机能有一定局限。依本研究结果我们推测：儿童单纯性肥胖这一表型可能为基因依赖性。Ｆｇ基因可能对此表型有一定程度的调控，此外，该基因可能与调控人类有氧能力的基因连锁。本研究的现实意义是：就Ｆｇ基因而言，不同基因型个体具有相异的健康风险阈值，某种等位基因的携带者可能在心肺机能方面具有一定程度的劣势。这不仅有助于对肥胖儿童的早期监护，而且还为运动员的早期筛选提供依据。 The Taq I restriction endonuclease site of fibrinogen (Fq) gene polymorphism is associated with simple obesity and maximum aerobic capacity in children. The risk of T1 homozygote obesity is high, and there are some limitations in heart and lung function. According to the results of our study, we speculate that the phenotype of childhood simple obesity may be gene-dependent. Fg gene may have a certain degree of regulation of this phenotype, in addition, the gene may be linked to genes regulating human aerobic capacity. The practical significance of this study is that individuals with different genotypes have different health risk thresholds for Fg genes and carriers of certain alleles may have some degree of inferiority in cardiopulmonary function. This not only contributes to the early guardianship of obese children, but also provides the basis for the early screening of athletes.