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目的探讨丹参酮ⅡA磺酸钠联合阿托伐他汀治疗冠心病的效果。方法选取冠心病患者110例,将其随机分为两组,每组55例。对照组给予阿托伐他汀治疗,观察组给予丹参酮ⅡA磺酸钠联合阿托伐他汀治疗。对比分析两组治疗效果、血脂水平及血流动力学指标。结果对照组治疗总有效率为81.8%,明显低于观察组的94.5%,差异有统计学意义(P<0.05);治疗后对照组低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)、总胆固醇(TC)值均明显高于观察组,但高密度脂蛋白胆固醇(HDL-C)明显低于观察组,差异有统计学意义(P<0.05);治疗后观察组血流动力学指标较对照组明显降低,差异有统计学意义(P<0.05)。结论给予冠心病患者丹参酮ⅡA磺酸钠联合阿托伐他汀治疗效果显著,可明显降低患者血压、血脂,恢复血流动力学水平,减少血栓及斑块形成,改善预后。
Objective To investigate the effect of tanshinone Ⅱ A sulfonate combined with atorvastatin on coronary heart disease. Methods 110 patients with coronary heart disease were selected and randomly divided into two groups, 55 cases in each group. The control group was given atorvastatin, and the observation group was given tanshinone Ⅱ A sulfonate combined with atorvastatin. The curative effect, blood lipid level and hemodynamics indexes of two groups were compared and analyzed. Results The total effective rate of the control group was 81.8%, which was significantly lower than 94.5% of the observation group (P <0.05). After treatment, the levels of LDL-C, triglyceride TG and TC were significantly higher than those of the observation group, but HDL-C was significantly lower than that of the observation group (P <0.05). After treatment, the blood flow of the observation group Kinetic index was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion The treatment of patients with coronary heart disease with tanshinone Ⅱ A sulfonate and atorvastatin treatment significantly, can significantly reduce the patient’s blood pressure, blood lipids, hemodynamic recovery, reduce thrombosis and plaque formation, improve prognosis.