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目的研究冠心病合并糖尿病,血糖水平对临床效果以及预后的影响。方法 102例冠心病合并糖尿病患者,调查基本资料;将102例患者随机分为A组(44例)与B组(58例),A组血糖≤7.0mmol/L,B组血糖>7.00 mmol/L,分析控制血糖对患者的临床效果以及预后影响。并对所选取的患者采用Logistic回归分析法,研究其产生冠心病合并心血管疾病的影响因素和不良事件发生情况。结果 A组与B组急性心肌梗死、血脂、纤维蛋白、死亡率以及心血管病变发生概率调查,其中A组急性心肌梗死12例、血脂10例、纤维蛋白8例、死亡7例、心血管病变7例;急性心肌梗死发生率为27.27%、血脂发生率为22.73%、纤维蛋白发生率为18.18%、死亡率为15.91%、心血管病变发生率为15.91%;B组急性心肌梗死28例、血脂9例、纤维蛋白9例、死亡6例、心血管病变7例,急性心肌梗死发生率为48.28%、血脂发生率为15.52%、纤维蛋白发生率为15.52%、死亡率为10.34%、心血管病变发生率为12.07%;另外经Logistic回归分析,心肌梗死的发生几率与血糖水平之间关系差异显著。B组患者的心肌梗死几率高于A组,且在总胆固醇、低密度脂蛋白、载脂蛋白B、尿蛋白阳性、左室舒张末内径和动脉完全闭塞状态高于A组,差异有统计学意义(P<0.05)。结论冠心病合并糖尿病患者需要对空腹血糖、血红蛋白以及餐后2 h血糖水平进行控制,以确保患者的临床治疗以及预后。
Objective To study the effect of coronary heart disease with diabetes mellitus and blood glucose level on clinical outcome and prognosis. Methods A total of 102 patients were randomly divided into group A (n = 44) and group B (n = 58). A group had a blood glucose of ≤ 7.0 mmol / L and a group B with a blood glucose> 7.00 mmol / L, analysis and control of blood glucose in patients with clinical effects and prognosis. Logistic regression analysis was used to analyze the influencing factors and occurrence of adverse events in CHD patients with CHD. Results The incidences of acute myocardial infarction, blood lipids, fibrin, mortality and cardiovascular diseases in group A and group B were investigated. Among them, 12 cases of acute myocardial infarction, 10 cases of lipids, 8 cases of fibrin, 7 cases of death, 7 cases. The incidence of acute myocardial infarction was 27.27%, the incidence of lipids was 22.73%, the incidence of fibrin was 18.18%, the mortality was 15.91%, and the incidence of cardiovascular disease was 15.91% 9 cases of lipids, 9 cases of fibrin, 6 cases of death, 7 cases of cardiovascular disease, acute myocardial infarction rate was 48.28%, blood fat rate was 15.52%, fibrin rate was 15.52%, the mortality rate was 10.34%, heart The incidence of vascular lesions was 12.07%. In addition, Logistic regression analysis showed that there was significant difference between the incidence of myocardial infarction and blood glucose level. The risk of myocardial infarction in group B was higher than that in group A, and the levels of total cholesterol, low density lipoprotein, apolipoprotein B, urinary protein, left ventricular end-diastolic diameter, and complete arterial occlusion were higher in group B than in group A Significance (P <0.05). Conclusion Patients with coronary heart disease complicated with diabetes need to control fasting blood glucose, hemoglobin and 2-hour postprandial blood glucose levels in order to ensure the clinical treatment and prognosis of patients.