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吊罗山地区为抗氯喹和喹哌的多重抗药性恶性疟流行区,自1986年起,凡恶性疟患者一律采用咯萘啶(咯),磺胺多辛(磺)和乙胺嘧啶(乙)复方治疗,并定时监测疟原虫对药物的敏感性。1990年6~9月,继续在该区采用体内4周法测定咯/磺/乙复方对当地恶性疟的治疗效应。材料与方法一、病例选择血检确诊的现症恶性疟患者,原虫密度在500/ul以上,半月内未用过抗疟药及磺胺类、四环素等,经伊红法测尿4-氨基喹啉类阴性者、收治观察。22例
Diao Luoshan area is chloroquine and quinacille multi-drug resistant Plasmodium falciparum endemic areas, since 1986, all the patients with falciparum malaria should be treated with pyronaridine, sulfadoxine and pyrimethamine, Compound treatment, and regular monitoring of the parasite’s drug sensitivity. From June to September 1990, we continued to use the 4-week method in vivo to determine the effect of treatment of local falciparum malaria in CSP / S / B regimen. Materials and methods First, the choice of blood samples diagnosed cases of falciparum malaria patients, the protozoa density of 500 / ul or more, did not use anti-malaria drugs and sulfa, half a month tetracycline and so on, measured by eosin urine 4-amino-quinoline Negative cases of morphine, admitted to observation. 22 cases