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目的:对108例晚期卵巢癌患者在治疗期间应用甘露聚糖肽序贯联合多西他赛、卡铂化疗方案进行治疗效果以及毒副反应分析。方法:收集自2012年4月~2016年10月在我院所接受治疗的108例晚期卵巢癌患者进行分析,随机分为观察组和对照组各54例,对照组:多西他赛、卡铂化疗方案治疗,观察组:对照组基础上进行甘露聚糖肽序贯治疗,记录和比较所有的患者在进行临床治疗过程中的治疗效果、生活质量。结果:观察组的患者在进行临床治疗过程中的治疗效果、生活质量等均优于对照组。差异有统计学意义,P<0.05。结论:对108例晚期卵巢癌患者在治疗期间应用甘露聚糖肽序贯联合多西他赛、卡铂化疗方案进行治疗效果以及毒副反应分析,提高治疗效果,临床价值大。
Objective: To treat 108 patients with advanced ovarian cancer during the treatment of mannan polysaccharide sequential combined with docetaxel, carboplatin chemotherapy for treatment and toxicity analysis. Methods: A total of 108 patients with advanced ovarian cancer who underwent treatment in our hospital from April 2012 to October 2016 were collected and randomly divided into observation group (54 cases) and control group (54 cases). The control group was docetaxel Platinum chemotherapy regimen, observation group: control group based on sequential mannan peptide treatment, record and compare all patients in the clinical treatment of the treatment effect, quality of life. Results: The treatment effect and quality of life of patients in the observation group were better than those in the control group. The difference was statistically significant, P <0.05. Conclusion: 108 cases of advanced ovarian cancer patients treated with mannan polysaccharide sequential combination of docetaxel, carboplatin chemotherapy for treatment and toxicity and side effects analysis, improve the therapeutic effect, clinical value.