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细胞免疫对粘膜衣原体感染所起的防御作用尚未明瞭。Sacks等曾用沙眼衣原体感染枭猴眼组织,观察到迟发型变态反应。迟发型变态反应的出现与结膜细胞内衣原体包涵体的清除相关,而局部或全身抗体则无明显关系。Rank等以豚鼠包涵体结膜炎因子感染豚鼠生殖器,发现抗胸腺细胞血清可抑制豚鼠的细胞免疫,延长感染期(处理后局部抗体的产生也延迟)。可见,细胞免疫可能有助于粘膜感染的清除。
The role of cellular immunity in the prevention of mucosal chlamydial infection remains unclear. Sacks et al. Used Chlamydia trachomatis to infect Opuntia oculi tissues, and late-onset hypersensitivity was observed. The appearance of delayed-onset allergy is associated with the clearance of inclusion bodies of C. subtilis in conjunctival cells, whereas there is no clear correlation between local and systemic antibodies. Rank such as guinea pig conjunctivitis factor infection in guinea pig genitalia found that anti-thymocyte serum can inhibit guinea pig cellular immunity, prolong the infection period (after the treatment of local antibody production is also delayed). Can be seen that cellular immunity may help clear the mucosal infection.