髓过氧化物酶(MPO)是位于粒细胞初级颗粒上的一种酶,通常认为是髓细胞特异性的。根据FAB分型建议,原始细胞中MPO阳性者≥3%即可诊断急性髓系白血病(AML)。近来,人们开始用多克隆或单克隆抗体对MPO进行免疫学检测。FAB协作组建议:当细胞化学阴性时可用上述方法检测 Myeloperoxidase (MPO) is an enzyme located on primary particles of granulocytes and is generally considered to be myeloid-specific. According to the FAB classification recommendation, acute myeloid leukemia (AML) can be diagnosed in patients with MPO positive ≥ 3% in primary cells. Recently, people have begun to immunologically test MPO with polyclonal or monoclonal antibodies. FAB Collaboration recommends that the above method be used when cytochemistry is negative