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探讨了泰兴地区人群肝癌的高发因素。采用ELISA法分别检测人群体内HBV感染水平和AFT—SHA含量及生活饮用水水体内MC含量。结果发现该地区人群HBsAg携带率为29.5%,HBV感染阳性率68.1%,肝癌高发乡镇人群HBsAg携带率和HBV感染阳性率分别高达45.8%和94.7%;人群体内AFT—HSA检出率达100%,平均含量为16.39pg/ng;高发乡镇人群体内AFT—HSA平均含量31.99pgM;生活饮用水水体内MC阳性检出率13.2%,河水、沟塘水和浅井水内MC的平均含量分别为36ng/L,29ng/L和25ng/L.结论:人群中的HBV高感染;黄曲霉素强暴露;生活饮用水水体内MC的普遍污染是泰兴地区肝癌高发的三个重要因素.
The high risk factors of liver cancer in Taixing population were discussed. ELISA was used to detect the level of HBV infection and AFT-SHA content in the human population and MC content in drinking water bodies. The results showed that the population carrying rate of HBsAg in the region was 29.5%, and the positive rate of HBV infection was 68.1%. The HBsAg carrier rate and HBV infection positive rate in townships with high incidence of hepatocellular carcinoma were as high as 45.8% and 94.7%, respectively; AFT-HSA in the human population. The detection rate was 100% with an average content of 16.39 pg/ng; the average AFT-HSA content was 31.99 pg in the population of high-income townships; the positive detection rate of MC was 13.2% in the drinking water bodies of drinking water, river water, and gully water. The average MC content in shallow wells was 36 ng/L, 29 ng/L and 25 ng/L, respectively. Conclusion: High HBV infection in the population; strong exposure to aflatoxin; widespread contamination of MC in drinking water bodies is an important factor in the high incidence of liver cancer in Taixing area.