Some macroreticular adsorption resins were used for decolorization of vitamin B6 in aqueous solution. The results show that the resins with higher specific surface have a higher decolorizing efficiency. The decolorizing process of resin AB 8 was more rapid. Resin H103 had high decolorizing efficiency, but wasnt easily regenerated. Treatment of crude Vitamin B6 solution by adsorbent ToH allows for multiple regeneration cycles without loss of decolorization properties. The decolorization of the crude Vitamin B6 was 85%. Some macroreticular adsorption resins were used for decolorization of vitamin B6 in aqueous solution. The results show that the resins with higher specific surface have a higher decolorizing efficiency. The decolorizing process of resin AB8 was more rapid. Resin H103 had high decolorizing efficiency, but wasnt easily regenerated. Treatment of crude Vitamin B6 solution by adsorbent ToH allows for multiple regeneration cycles without loss of decolorization properties. The decolorization of the crude Vitamin B6 was 85%.