5%等渗葡萄糖注射液是医院大输液生产中常见的一种制剂。我院过去生产此种输液,经药检所测定,往往含量偏高。据了解其它一些医院也存在类似问题。含量偏高的主要原因是投料问题,而投料问题又源于各种书籍对其含量规定不同。许多教科书和制剂手册都规定其含量5%是指无水葡萄糖5%。例如《药剂学》〔南京药学院主编:295页,人民卫生出版社,1978〕一书中指出:本品之5%者药典规定为无水物的含量而不是含一个分子的结晶水者。《药剂学》〔全国中等卫生学校统编教材《药剂学》编写组:第13章79页,江西省卫生 5% isotonic glucose injection is a common infusion formulation in hospitals. Our hospital in the past to produce such infusion, determined by drug testing, often high content. It is understood that there are other similar problems in some hospitals. The main reason for the high content is the feeding problem, and the feeding problem originates from the different kinds of books. Many textbooks and preparation manuals specify that 5% of its content refers to 5% anhydrous glucose. For example, “Pharmacy” [Nanjing Pharmaceutical College editor: 295 pages, People’s Health Publishing House, 1978] a book that: 5% of the goods pharmacopoeia for the anhydrous content rather than containing a molecule of crystal water. “Pharmacy” [National secondary health school teaching materials compiled “Pharmacy” writing group: Chapter 13 79, Jiangxi Province Health