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目的 探讨无水乙醇顺行性淋巴结封闭对肺部恶性肿瘤转移的影响。方法 随机选择72例肺癌患者在术中按照Naruke 肺癌淋巴结分布图, 用无水乙醇注射该病种最易转移的区域淋巴结。另选择TNM相似的肺癌患者, 采用常规手术方法进行手术。术后复查血液中乙醇含量、肝功及复查CT了解注射淋巴结肿大情况, 对两组病例进行统计分析。结果 全组无手术死亡。术后血常规、肝功能、免疫球蛋白等均未见明显异常, 两组乙醇含量比较差异无显著意义(P>0.05), 实验组与对照组生存率比较差异有显著意义(P<0.05)。结论 无水乙醇顺行性淋巴结封闭对肺癌转移有较大的影响, 能够达到比较理想的淋巴结清扫目的。
Objective To investigate the effect of anhydrous ethanol on lymph node metastasis of lung cancer. Methods 72 patients with lung cancer were randomly selected according to Naruke lung cancer lymph node distribution map, the most easily transmissible regional lymph nodes with ethanol injection. Another choice of TNM similar lung cancer patients, using conventional surgical methods for surgery. Postoperative review of blood alcohol content, liver function and review CT to understand the situation of injection of lymph nodes, the two groups of patients for statistical analysis. Results All patients died without surgery. Postoperative blood, liver function, immunoglobulin and other no significant abnormalities, ethanol content was no significant difference between the two groups (P> 0.05), the experimental group and the control group were significantly different survival rates (P <0.05) . CONCLUSIONS: Antiretachment of ethanol on paraffin-embedded lymph nodes has a significant effect on the metastasis of lung cancer and can achieve ideal lymphadenectomy.