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目的了解镇静催眠及抗焦虑药在北京的应用情况。方法采用世界卫生组织推荐的限定日剂量为指标的分析方法,对北京36家医院2005～2007年镇静催眠药及为抗焦虑药的应用进行药物利用评价与分析。结果苯二氮革类药的用药频度(DDDs)3年中所占比例都在70%以上,占了主导地位,这表明药物应用频度过大,提示有一定滥用倾向。结论苯二氮革类(BDZ)药物是治疗睡眠障碍的主导药,而非苯二氮革类(NBDZ)也逐渐被临床所接受,但BDZ类药物滥用倾向值得警惕。
Objective To understand the application of sedative, hypnotic and anti-anxiety drugs in Beijing. Methods According to the recommended daily limit of dosage recommended by the World Health Organization (WHO), the sedation and hypnotics in 36 hospitals in Beijing from 2005 to 2007 were evaluated and analyzed for their anti-anxiety drug use. Results The dosage of benzodiazepines (DDDs) accounted for more than 70% in 3 years, which indicates that the frequency of drug use is too large, suggesting a certain abuse tendency. Conclusion Benzodiazepines (BDZ) drugs are the leading drugs in the treatment of sleep disorders, while non-benzodiazepines (NBDZ) are gradually accepted by the clinic. However, BDZ drugs should be used with caution.