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目的探讨彩色多普勒超声对乳腺癌新辅助化疗疗效评价的临床价值。方法采用彩色多普勒超声评价55例行新辅助化疗的乳腺癌患者的疗效和血流动力学。结果彩超检查有效率(65.45%)与病理组织学有效率(69.09%)比较差异未见统计学意义(P>0.05),符合率为78.19%,敏感度为81.58%。有效组治疗前后血流等级变化比较差异有统计学意义(P<0.01),病灶内血流Vmax和RI比较差异均有统计学意义(P<0.05)。结论彩色多普勒超声能真实反应乳腺癌新辅助化疗疗效,同时能准确检测病灶区域血流动力学的改变。
Objective To investigate the clinical value of color Doppler ultrasound in the evaluation of the efficacy of neoadjuvant chemotherapy for breast cancer. Methods Color Doppler echocardiography was used to evaluate the efficacy and hemodynamics of 55 patients with neoadjuvant chemotherapy for breast cancer. Results There was no significant difference between color Doppler ultrasound examination (65.45%) and pathological histology (69.09%) (P> 0.05). The coincidence rate was 78.19% and the sensitivity was 81.58%. There were significant differences in blood flow changes between the effective group before and after treatment (P <0.01), and there were significant differences in the Vmax and RI between the two groups (P <0.05). Conclusion Color Doppler ultrasound can truly reflect the effect of neoadjuvant chemotherapy in breast cancer and can accurately detect hemodynamic changes in the lesion area.