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目的观察单纯翼状胬肉切除、胬肉切除联合丝裂霉素治疗与胬肉切除加自体角膜缘上皮联合球结膜移植治疗翼状胬肉的临床疗效。方法选择符合手术标准的翼状胬肉患者93例112只眼,分为A(38眼)、B(38眼)、C(36眼)三组。A组翼状胬肉单纯切除,B组胬肉切除联合丝裂霉素治疗,C组胬肉切除加自体角膜缘上皮联合球结膜移植。观察三组术后角结膜愈合情况以及胬肉复发率。结果随访12～30月,复发率A组23.68%,B组10.53%,C组无复发病例。C组与A、B组比较,差异均有统计学意义(P<0.05)。结论 胬肉切除加角膜缘干细胞联合结膜移植是处理胬肉复发的最佳方式。该手术较简便,成功率高,复发率低。
Objective To observe the clinical efficacy of simple pterygium excision, pterygium excision combined with mitomycin and pterygium excision plus autologous limbal epithelium combined with conjunctival transplantation for the treatment of pterygium. Methods A total of 112 eyes of 93 patients with pterygium were enrolled and divided into three groups: A (38 eyes), B (38 eyes) and C (36 eyes). A group of pterygium simple excision, B group pterygium excision combined with mitomycin C group pterygium excision plus autologous limbal epithelial conjunctiva transplantation. The postoperative conjunctival healing and the recurrence rate of pterygium were observed. Results The patients were followed up for 12-30 months. The recurrence rate was 23.68% in group A and 10.53% in group B, respectively. There was no recurrence in group C There was significant difference between group C and group A and B (P <0.05). Conclusions Pterygium resection plus limbal stem cells combined with conjunctival transplantation is the best way to deal with the recurrence of pterygium. The surgery is relatively simple, high success rate, low recurrence rate.