新生儿缺氧缺血性脑病(HIE)是新生儿死亡及儿童神经系统发育障碍和导致产生神经系统后遗症的重要原因。该病的发病机理多数人认为与缺氧引起的代谢紊乱、氧自由基的变化有关。在妊娠后期至一岁前,神经系统最活跃,脑的耗氧量占全身耗氧量的一半,一旦发生脑组织缺氧缺血,必将影响神经系统的正常活动,并导致脑水肿及脑梗塞。现将我们1994～1995年收治的57例报告如下。 Neonatal hypoxic-ischemic encephalopathy (HIE) is an important cause of neonatal death and neurodevelopmental disorders in children and neurological sequelae. Most of the pathogenesis of the disease that hypoxia caused by metabolic disorders, changes in oxygen free radicals. In the second trimester of pregnancy to the age of one, the nervous system is the most active, the brain’s oxygen consumption accounts for half of the body’s oxygen consumption, in the event of hypoxic-ischemic brain tissue, will certainly affect the normal nervous system activity and lead to cerebral edema and brain infarction. Now we admitted from 1994 to 1995 57 cases are as follows.