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目的探究消疹清心汤加减对手足口病(HFMD)合并心肌受损患儿的临床治疗效果。方法根据入院时间将本院收治的86例HFMD合并心肌受损患儿随机分成两组,各43例,对照组行常规抗病毒、保护心肌等对症治疗;观察组在此基础上加用自拟消疹清心汤治疗,比较两组疗效及相关临床指标变化。结果 1观察组有效率为95.35%,高于对照组的79.07%(P<0.05);2观察组疗程、皮疹消退及退热时间均短于对照组(P<0.01);3治疗后,观察组心电图总异常率低于对照组(P<0.05);4治疗后,观察组血清肌钙蛋白及心肌酶水平均低于对照组(P<0.01)。结论消疹清心汤加减治疗可减轻HFMD患儿临床症状,改善患儿心肌酶水平,临床疗效确切,值得应用。
Objective To investigate the clinical efficacy of “Decoction of Eliminating Erease Qingxin Decoction” in children with hand-foot-mouth disease (HFMD) complicated with myocardial damage. Methods According to the admission time, 86 HFMD patients with myocardial infarction admitted to our hospital were randomly divided into two groups (n = 43, n = 43 each). The control group received conventional antiviral therapy to protect the myocardium against symptomatic treatment. The observation group was self-prepared Erasing clear heart soup treatment, the two groups compared the efficacy and changes in relevant clinical indicators. Results 1 The effective rate of the observation group was 95.35%, which was higher than 79.07% of the control group (P <0.05) .2 The course of treatment, rash subside and the time of fever relief were shorter in the observation group than in the control group (P <0.01) (P <0.05). After 4 treatments, the levels of serum troponin and myocardial enzymes in the observation group were lower than those in the control group (P <0.01). Conclusion Decoction of Decoction of Eliminating Ease Qingxin Decoction can alleviate the clinical symptoms of children with HFMD and improve the level of myocardial enzymes in children. The clinical curative effect is worthy of application.