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近年,很多医院已在使用免疫疗法治疗习惯性流产。但是,其治疗效果因医院不同而有若干差异,其原因在于治疗对象的选择有所差异和未能严密地实行判定方法。一、习惯性流产的免疫学和免疫疗法从移植免疫学角度看妊娠现象,认为胎儿是具有父系抗原的同种移植物(allograft),理应因母体的免疫反应而发生排斥。但是,实际上在正常妊娠时并不引起排斥反应,即母体对胎儿产生耐受,提示存在某种免疫学的妊娠维持机制。有时这种免疫学的妊娠维持机制未能很好地起作用,引起排斥反应而反复流产,即习惯性流产(免疫学的习惯流产)。对免疫学的习惯性流产的免疫疗法,在于抑制患者对其丈
In recent years, many hospitals have been using immunotherapy to treat habitual abortion. However, the therapeutic effects vary somewhat from hospital to hospital because of differences in the choice of treatment and failure to enforce the test. First, the immunology and immunotherapy of habitual abortion from the immunological perspective of pregnancy, pregnancy, that the fetus is a paternally-derived allograft (allograft), should be due to the mother’s immune response and rejection. However, in practice, rejection does not arise in normal pregnancy, ie, maternal tolerance to the fetus suggests that there is some immunological mechanism of pregnancy maintenance. Sometimes this immunological mechanism of pregnancy maintenance does not work well, causing rejection and recurrent miscarriage, habitual abortion (immunological habitual abortion). Immunotherapy of habitual abortion immunotherapy, is to suppress the patient’s husband