患者,男性,70岁,4周来出现厌食、体重减轻、发热达102°F(38.9℃)。体检无异常。实验室检查有氮质血症,脓尿、多克隆γ-球蛋白病、碱性磷酸酶水平升高、血小板增多。所有培养均为阴性。上述症状发生前,患者因慢性返流性食管炎服甲腈咪胍,每天4次,每次300mg,共5天,然后睡前服 Patients, men, were 70 years old and had anorexia and weight loss 4 weeks later, with fever of 102 ° F (38.9 ° C). No abnormal medical examination. Laboratory tests with azotemia, pyuria, polyclonal γ-globulin disease, elevated levels of alkaline phosphatase, thrombocytosis. All cultures were negative. Before the occurrence of the above symptoms, patients with chronic reflux esophagitis with nitrileidine, 4 times a day, each 300mg, a total of 5 days, and then before going to bed