自60年代开始用羊膜腔穿刺抽取羊水进行羊水细胞培养技术检查染色体核型成功以来,对染色体遗传性疾病的产前诊断要在妊娠中期16～20周进行。因此,确诊为染色体异常胎儿的处理须行妊娠中期引产术,这对孕妇有一定的痛苦和危险。近年来,国内外许多学者经过不断探索已将产前诊断提早到 Since the 1960s, amniocentesis has been performed for amniocentesis and amniotic fluid cell culture to check the success of chromosome karyotypes. The prenatal diagnosis of genetic chromosomal diseases should be performed at 16 to 20 weeks of gestation. Therefore, the diagnosis of chromosomal abnormalities in the fetus should be treated during the second trimester induction of labor, which pregnant women have some pain and danger. In recent years, many scholars both at home and abroad have made prenatal diagnosis earlier