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目的 考察蕲蛇酶对急性脑梗死的治疗效果。方法 将１９０例急性脑梗死患者随机分成蕲蛇酶治疗组９６例，对照组９４例，进行双盲对照研究。结果 蕲蛇酶治疗组显效率为６７．７％ ，较对照组之４６．８％ 明显升高（Ｐ＜ ０．０１）；治疗后ＦＧ、ＰＡｇＴ、ｎＰ、Ｈｔ４项凝血指标显著下降（Ｐ＜ ０．０５）；颅脑ＣＴ复查低密度灶平均体积显著小于对照组（Ｐ＜ ０．０１）。结论 蕲蛇酶实为一种新型的降纤、抗栓、改善微循环的药物。
Objective To investigate the therapeutic effect of Acutobin on acute cerebral infarction. Methods A total of 190 patients with acute cerebral infarction were randomly divided into acutase treatment group (n = 96) and control group (n = 94) for double-blind controlled study. Results The apparent efficiency of Acanthopanax enzyme treatment group was 67.7%, which was significantly higher than 46.8% of control group (P <0.01). The coagulation indexes of FG, PAgT, nP and Ht4 decreased significantly after treatment (P < 0.05). The average volume of low density lesions in CT scan was significantly smaller than that in control group (P <0.01). Conclusion Viper enzyme is a new type of anti-fibrosis, antithrombotic, microcirculation drugs.