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一、病原学、发病学: 单纯庖疹性角膜炎(以下简称单疱性角膜炎)由Ⅰ型单纯疱疹病毒(以下简称单疱病毒)感染所引起。人类是单疱病毒唯一的自然宿主。Ⅰ型单疱病毒主要侵犯角膜、结膜、皮肤、口唇粘膜、中枢神经系统等表面外胚叶及神经外胚叶组织。单疱病毒的初感染多发生于6~24个月的婴儿,可能因为此时得自母体的获得性免疫力比初生时已明显降低的缘故。现已证明,7~24个月婴儿唾液中有
First, the etiology, pathogenesis: simplex rash keratitis (hereinafter referred to as unilateral keratitis) is caused by herpes simplex virus type I (hereinafter referred to as herpes simplex virus) infection. Humans are the only natural hosts of herpes simplex virus. Type I herpes simplex virus mainly affects the cornea, conjunctiva, skin, lip mucosa, central nervous system and other surface ectodermal and neuroectodermal tissues. Initial infection with herpes simplex virus occurs mostly in infants 6 to 24 months, probably because acquired immunity from the mother is significantly lower than at birth. It has been proved that 7 to 24 months in baby saliva