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目的探讨2型糖尿病(T2DM)微血管病变患者C反应蛋白(CRP)与血浆D-二聚体(D-dimer)水平变化。方法 89例2型糖尿病患者根据糖化血红蛋(HbAlc)检测结果分为两组,即HbAlc≤6%的单纯糖尿病组46例和HbAlc>6%的糖尿病微血管病变组43例,对C反应蛋白、血浆D-二聚体进行检测与分析。结果 HbAlc>6%组C反应蛋白、D-二聚体与HbAlc≤6%组比较差异有统计学意义(P<0.01)。结论糖化血红蛋白、C反应蛋白和D-二聚体检测对2型糖尿病患者血糖控制情况及微血管病变的预防具有重要意义。
Objective To investigate the changes of C-reactive protein (CRP) and plasma D-dimer in patients with type 2 diabetes mellitus (T2DM) microangiopathy. Methods Eighty-nine patients with type 2 diabetes mellitus were divided into two groups based on HbAlc test: 46 patients with HbAlc≤6% and 43 patients with HbAlc> 6% diabetic microangiopathy. The levels of C-reactive protein, Plasma D-dimer was tested and analyzed. Results HbAlc> 6% group C-reactive protein, D-dimer and HbAlc≤6% group difference was statistically significant (P <0.01). Conclusions The detection of HbA1c, C-reactive protein and D-dimer is of great significance for the prevention of type 2 diabetes mellitus and the prevention of microvascular disease.