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目的探讨腹腔镜保留输卵管术对输卵管妊娠患者卵巢储备功能及生育功能的影响。方法选取2015年5月-2016年5月华中科技大学附属同济医院收治的125例患者为研究对象,均给予腹腔镜保留输卵管术治疗,将其纳入研究组,选取同期入院的75例纳入对照组,给予腹腔镜输卵管切除术治疗,比较两组患者治疗效果。结果随访半年发现,研究组的激素水平卵泡刺激素(FSH)(6.2±1.1)U/L、黄体生长素(LH)(5.8±1.2)U/L、抗苗勒氏管激素(AMH)(3.6±1.5)μg/L均优于对照组[(8.1±1.2)U/L、(6.9±1.5)U/L、(1.8±1.2)μg/L],差异有统计学意义(t=4.633、4.765、5.345,P<0.05);卵巢储备功能指标窦卵泡数(15.3±4.4)个、卵巢横截面积(4.1±1.2)cm~2优于对照组[(12.3±3.4)个、(3.8±1.5)cm~2],差异有统计学意义(t=4.753、4.532,P<0.05);研究组的排卵率(77.60%)与妊娠率(70.40%)均高于对照组(53.33%、30.67%),差异有统计学意义(χ~2=12.793、29.964,P<0.05)。结论输卵管妊娠患者经腹腔镜保留输卵管术治疗,保护了其卵巢储备功能及生育功能,值得推广。
Objective To investigate the effect of laparoscopic preservation of oviduct on ovarian reserve and reproductive function in patients with tubal pregnancy. Methods From May 2015 to May 2016, 125 patients admitted to Tongji Hospital Affiliated to Huazhong University of Science and Technology were enrolled in this study. All patients were treated with laparoscopy to retain tubal, which was included in the study group. 75 patients admitted to the same period were included in the control group , To give laparoscopic tubal resection treatment, the treatment effect of two groups were compared. Results Six months after the study, the levels of FSH (6.2 ± 1.1) U / L, LH (5.8 ± 1.2) U / L and AMH in the study group 3.6 ± 1.5) μg / L were significantly higher than those in the control group [(8.1 ± 1.2) U / L, (6.9 ± 1.5) U / L, , 4.765,5.345, P <0.05). The ovarian reserve index of antral follicles (15.3 ± 4.4) and ovary (4.1 ± 1.2) cm ~ 2 were superior to those of the control group [(12.3 ± 3.4) ± 1.5) cm ~ 2, the difference was statistically significant (t = 4.753,4.532, P <0.05). The ovulation rate and pregnancy rate of the study group were significantly higher than those of the control group (77.60% vs. 70.40%, 53.33% 30.67%), the difference was statistically significant (χ ~ 2 = 12.793,29.964, P <0.05). Conclusion Tubal pregnancy by laparoscopy retained tubal treatment, to protect their ovarian reserve function and reproductive function, it is worth promoting.