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目的分析急性脑梗死患者采用醒脑静注射液治疗中对血清白细胞介素-6(IL-6)、白细胞介素-12(IL-12)的影响性分析。方法选取信宜市人民医院2014年6月-2016年6月收治的急性脑梗死患者140例,随机分为对照组和观察组各70例,对照组给予患者进行西医常规治疗,观察组在对照组的基础上,再给予进行醒脑静注射液,比较两组患者治疗后的IL-6、IL-12的变化以及神经功能的状况。结果治疗后对照组神经功能评分为(16.72±2.56)分,观察组的神经功能损伤为(9.41±2.66)分,对照组高于观察组,差异有统计学意义(P<0.05);治疗后对照组的总有效率为82.9%,观察组的总有效率为94.3%,对照组低于观察组,差异有统计学意义(P<0.05)。结论给予急性脑梗死患者进行醒脑静注射液治疗,可以降低IL-6、IL-12的水平,改善脑功能,有利于患者康复,应用价值高,值得在临床上推广使用。
Objective To analyze the influence of Xingnaojing injection on serum interleukin-6 (IL-6) and interleukin-12 (IL-12) in patients with acute cerebral infarction. Methods 140 patients with acute cerebral infarction who were treated in Xinyi People’s Hospital from June 2014 to June 2016 were randomly divided into control group and observation group with 70 cases in each group. Patients in control group were given conventional western medicine treatment. In observation group, On the basis of the group, we then administered Xingnaojing injection to compare the changes of IL-6, IL-12 and neurological function after treatment in both groups. Results After treatment, the score of neurological function in the control group was (16.72 ± 2.56) points, and the neurological impairment in the observation group was (9.41 ± 2.66) points, which was significantly higher in the control group than in the observation group (P <0.05) The total effective rate of the control group was 82.9%, the total effective rate of the observation group was 94.3%, the control group was lower than the observation group, the difference was statistically significant (P <0.05). Conclusions The treatment of Xingnaojing injection in patients with acute cerebral infarction can reduce the levels of IL-6 and IL-12, improve brain function, is beneficial to the rehabilitation of patients, and has high application value. It is worth to be used clinically.