Traditional climate classification or regionaliza-tion characterizes the mean state of climate condition, which cannot meet the demand of addressing climate change cur-rently. We have developed a climate change classification method, as well as the fundamental principles, an indicator system, and mapping techniques of climate change region-alization. This study used annual mean temperature and total precipitation as climatic indices, and linear trend and vari-ation change as change indices to characterize climate change quantitatively. The study has proposed a scheme for world climate change regionalization based on a half century of climate data (1961–2010). Level-I regionalization divides the world into 12 tendency zones based on the linear trend of climate, level-Ⅱ regionalization resulted in 28 fluctuation regions based on the variation change of climate. Climate change regionalization provides a scientific basis for coun-tries and regions to develop plans for adapting to climate change, especially for managing climate-related disaster or environmental risks.