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观察7条狗起搏前后从卧位变为站位时的血流动力学变化。起搏后起立时平均动脉压平均下降28％,是正常时(13％)的二倍,并且恢复时间明显延长(P<0.01)。实验表明起搏前后狗的体位性低血压代偿机制不同,正常时起立时心输出量增加20％左右,心率平均增加24％,而每搏输出量在开始阶段常减少,有的在整个站立过程中减少。心率在提高心输出量,代偿体位性低血压中起着重要作用。起搏后由于心率固定不变,因而出现明显的体位性低血压。提高起搏频率可改善体位性低血压。
The hemodynamic changes of 7 dogs before and after pacing were observed. Mean patency decreased by 28% on pacing from standstill, which was double that of normal (13%), and the recovery time was significantly longer (P <0.01). Experiments show that dogs with pacing before and after the different mechanism of orthostatic hypotension compensation, normal rise in cardiac output increased by about 20%, an average increase of 24% heart rate, and stroke volume often decreased in the initial stage, and some stand in the whole Reduce the process. Heart rate in improving cardiac output, compensatory orthostatic hypotension plays an important role. After pacing due to fixed heart rate, resulting in significant orthostatic hypotension. Improve the pacing rate can improve orthostatic hypotension.