双白瑞香素(Daphnoretin)为双香豆素衍生物。近来发现,该化合物对小鼠体内试验有抗癌活性,能抑制艾氏腹水癌,并具有抑制多种酶包括艾氏腹水癌细胞中DNA 合成的能力,因此重新引起关注。双白瑞香素主要存在于瑞香科植物中,豆科和芸香料中亦有分布(见表1) Daphnoretin is a dicoumarol derivative. Recently, it has been found that the compound has anticancer activity against mice in vivo, inhibits Ehrlich ascites carcinoma, and has the ability to inhibit DNA synthesis in a variety of enzymes, including Ehrlich ascites cancer cells, thus attracting renewed attention. Diclofenac is mainly present in Daphne plants, and is also found in legumes and rutaceae (see Table 1)