论文部分内容阅读
感染过程中脂质代谢紊乱被认为是由某些细胞因子如干扰素(IFN)、肿瘤坏死因子(TNF)、白细胞介素-1(IL-1)等免疫调节因子造成。AIDS的特征表现在高甘油三酯血症,循环中细胞因子水平升高以及进行性组织消耗等方面。作者通过测定AIDS患者及HIV阳性对象血清中上述因子,以期了解它们与血清甘油三酯及组织消耗之间的关系。病例和方法,检测血清分别来自45例AIDS患者,13例HIV阳性对象及17例阴性对照。α-IFN采用特异性抗体进行检测,TNF
Lipid metabolism disorders during infection are thought to be caused by certain cytokines such as interferon (IFN), tumor necrosis factor (TNF), interleukin-1 (IL-1) and other immunomodulatory factors. AIDS is characterized by hypertriglyceridemia, elevated circulating cytokine levels, and progressive tissue depletion. The authors determined the above factors in sera from AIDS patients and HIV-positive subjects in order to understand their relationship with serum triglycerides and tissue depletion. Cases and methods, serum samples from 45 cases of AIDS patients, 13 cases of HIV-positive and 17 cases of negative control. α-IFN was detected using specific antibodies, TNF