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目的：探讨胱抑素C与尿微量蛋白及尿酶联合检测在肾病治疗中的应用。方法78例来院的体检者，分为健康组、无症状肾病组、有症状肾病组，检测患者的Cys C、mAlb、 UREA。结果无症状肾病组和有症状肾病组的Cys C、mAlb、 UREA与健康组相比都有升高，健康组与无症状肾病组的 CysC和 mAlb差异具有统计学意义（P0.05）；健康组与有症状肾病组的 Cys C、mAlb、UREA差异具有统计学意义（P<0.05）；健康组的 Cys C、mAlb、UREA阳性率均为0，肾病组的阳性率分别为66.33％、41.56％、35.85％；Cys C+mAlb的阳性率为69.71%，Cys C+mAlb+UREA的阳性率为86.95%，联合阳性率大于单一检测的阳性率。结论肾病中胱抑素C与尿微量蛋白及尿酶联合检测能够提高诊断率，为治疗打好基础。“,”Objective:To investigate the application of cystatin C and urine protein andurine enzyme in the combined detection of nephropathy in. Methods: the physical examination in 78 caseswere dividedinto group, healthy,asymptomatic nephropathygroup, symptomatic nephropathy group were detected C, Cys, mAlb, UREA. Results:asymptomatic nephropathygroup and symptomatic nephropathy group Cys C, mAlb, UREA compared with the healthy group have increased, health group and a symptomatic renal group Cys C and mAlb, the dif erence was statistical y significant (P< 0.05), the re was no significant dif erence of UREA (P> 0.05); health group and symptomatic nephropathy group Cys C, mAlb, UREA, the dif erence was statistical y significant (P< 0.05); Cys C,mAlb health group, UREApositive ratewas, the positiverate of nephropathygroup were 66.33%, 41.56%, 35.85%;the positiverate of Cysin C+mAlbwas69.71%, positiverate of Cys C+mAlb+UREA 86.95%the positiverate of combined,positive rate higher than the single detection. Conclusion: nephropathy cystatin C and urinary protein and urinary enzyme combined detection can improve the diagnosis rate,lay a good foundation for treatment.