2型糖尿病中枢神经系统及血浆生长抑素水平对认知功能的影响越来越受到关注，生长抑素可能通过本身对中枢神经系统的调节，或通过胰岛素、 Aβ代谢等机制参与认知功能障碍的发生、发展，近年来临床证据表明生长抑素可能是轻度认知功能障碍的保护因素，早期识别认知功能障碍并使用生长抑素进行有效干预具有重要意义。“,”The effect of somatostatin in the central nervous system and peripheral blood plasma of patients with type 2 diabetes on cognition is more attented. Somatostatin involves in the occurrence and development of cognitive impairment by regulating the central nervous system or through insulin and A beta metabolic mechanism. In recent years clinical evidence has shown that somatostatin may be a protective factor for cognitive dysfunction. It is an important that early recognition of cognitive dysfunction and to give an effective intervention with somatostatin.