论文部分内容阅读
对１２６例血液病患者ＨＣＶ和ＨＢＶ感染及其病毒复制进行了研究。结果：①１２６例患者中ＨＣＶ抗体阳性８例（６．４％），大约比献血员感染率高１０倍（Ｐ＜０．０１）；在抗体阳性者中有７例ＨＣＶ－ＲＮＡ阳性（８７．５％）。②所测患者中ＨＢＶ五项标志物单项或多项阳性２６例（２０．６％），其中ＨＢＶ－ＤＮＡ阳性１２例（４６．２％）；在８例ＨＣＶ感染者中有３例与ＨＢＶ重叠感染（３７．５％），５例有既往输血史（６２．５％），４例ＡＬＴ异常（５０．０％）。研究表明，血液病患者中存在着较高的ＨＣＶ和ＨＢＶ感染以及病毒复制，应采取有效措施控制肝炎病毒的传播。
HCV and HBV infection and their virus replication in 126 patients with hematological diseases were studied. RESULTS: Among the 126 patients, 8 were positive for HCV antibody (6.4%), about 10 times higher than that of blood donors (P <0.01), and 7 were positive for HCV RNA in antibody positive patients (87). 5%). (2) 26 (20.6%) single or multiple HBV markers were detected in the tested patients, of which 12 were HBV-DNA positive (46.2%); 3 of 8 HCV-infected patients were positive for HBV Overlap infection (37.5%), 5 had a history of previous transfusions (62.5%), and 4 had ALT abnormalities (50.0%). Studies have shown that patients with hematological diseases have high HCV and HBV infection and virus replication, and effective measures should be taken to control the spread of hepatitis virus.