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以碳酸亚铊10mg/kg经口给大鼠灌胃染毒,5分钟后,可在大部份组织中测到铊;半小时,除胃以外,肝中含量最高;1小时后,除胃以外,脾和肾中含量最高,次为心和睾丸;2小时肾中浓度居首位,其高峰期在4~8小时;4小时后,骨中含量增高,仅次于胃、脑、肌肉。皮、血、毛中含量较低。铊主要经胃肠道及肾排出,24小时,大便排出染毒剂量的7.93%,尿排出5.17%。毛是铊排泄的缓慢途径。
Thallium was detected in most of the tissues 5 minutes after oral administration of thalidomide 10 mg / kg. After 1 hour, except for the stomach, the content of liver was the highest. After 1 hour, In addition, spleen and kidney in the highest content, followed by heart and testicle; 2 hours renal concentration in the first place, the peak in 4 to 8 hours; 4 hours later, increased bone content, second only to the stomach, brain, muscle . Skin, blood, hair content is lower. Thallium was mainly excreted through the gastrointestinal tract and the kidneys. After 24 hours, stool was discharged at a dosage of 7.93% and urine was discharged at 5.17%. Hair is a slow way to thallium excretion.