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目的：评价国产克林霉素磷酸酯的临床疗效和安全性。方法：细菌感染病人６０例（男性３９例，女性２１例；年龄４６±ｓ１７ａ），其中呼吸道感染４９例，尿路感染４例，皮肤软组织感染和急性骨髓炎各３例，败血症１例。用克林霉素磷酸酯１．２～２．４ｇ／ｄ，分２～３次静脉滴注，疗程７～１４ｄ。结果：治疗后临床有效率８５％，痊愈率６２％，细菌清除率９０％，不良反应少而轻微，皮疹和一过性ＡＬＴ升高的发生率分别为５％和２％。结论：国产克林霉素磷酸酯治疗需氧革兰阳性菌感染疗效好且安全。
Objective: To evaluate the clinical efficacy and safety of domestic clindamycin phosphate. Methods: Sixty patients with bacterial infection (39 males and 21 females; age 46 ± s17a), including 49 respiratory tract infections, 4 urinary tract infections, 3 skin soft tissue infections and 3 acute osteomyelitis cases and 1 sepsis. With clindamycin phosphate 1.2 ~ 2.4g / d, divided into 2 or 3 intravenous infusion, treatment 7 ~ 14d. Results: After treatment, the clinical effective rate was 85%, the cure rate was 62%, the bacterial clearance rate was 90%, the adverse reactions were mild and slight, and the rash and transient ALT were 5% and 2% respectively. Conclusion: Domestic clindamycin phosphate is effective and safe for the treatment of aerobic gram-positive bacteria.