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关于睡眠呼吸暂停(OSA)的发病机理,各界说法不一。有人以肌电图测定睡眠时颏舌肌的功能,发现吸气期颏舌肌轻度外突以保持气道通畅,因此设想OSA可能是颏舌肌功能受损、吸气时舌根脱垂,与咽后壁抵触之故。也有人通过实验,发现在出现呼吸道阻塞症状之前,呼吸的神经冲动和膈肌运动均见减退,因此认为OSA的发生与神经和肌肉等因素有关。OSA亦可能是吸气时咽部负压大大超过使上呼吸道扩张的肌肉的张力的结果;也有认为鼻阻塞可增加呼吸道之阻力,使吸气费力,并因负压而使气道萎陷遂
With regard to the pathogenesis of sleep apnea (OSA), various opinions vary. Some people to determine the function of the genioglossus during sleep, and found that during inspiratory genioglossus mild external protrusion to maintain airway patency, it is assumed that OSA may be impaired genioglossus, tongue socket prolapse, And the posterior wall of the pharynx conflict. Some people also found that in the presence of respiratory obstruction symptoms, respiratory and diaphragmatic nerve impulses were decreased, so that the occurrence of OSA and nerve and muscle and other factors. OSA may also be the result of inspiratory pharyngeal negative pressure that greatly exceeds that of the muscles that dilate the upper respiratory tract; there is also the suggestion that nasal obstruction increases the resistance of the respiratory tract, causing inspiratory effort and causing collapse of the airway due to negative pressure