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本文报告2例急性砷中毒患者,在进行常规催吐、洗胃、导泻、保肝、利尿等措施后,又应用二巯基丁二酸口服治疗。成功地救治了2名急性重度砷中毒患者。并在治疗前、治疗中及治疗后动态观察了患者晨尿砷浓度及24h尿砷含量的变化,结果表明:二巯基丁二酸治疗急性砷中毒,患者尿中排砷量增加,尤以急性中毒早期更为明显;晨尿砷含量的变化与24h尿砷量的变化基本一致;晨尿砷含量有可能替代24h尿砷含量的监测。
This article reports 2 cases of acute arsenic poisoning patients, in the conventional emetic, gastric lavage, catharsis, liver, diuretic and other measures, but also the application of dimercaptosuccinic acid oral treatment. Two patients with acute severe arsenic poisoning were successfully treated. The changes of arsenic concentration in morning urine and urine arsenic in 24 hours were observed before treatment, during treatment and after treatment. The results showed that the concentration of arsenic in urine increased with the treatment of dimercaptosuccinic acid, especially in acute The early poisoning was more obvious. The change of arsenic content in morning urine was basically consistent with the change of 24-hour urine arsenic content. The morning urine arsenic content may be a substitute for 24h urinary arsenic content monitoring.