我厂生产的强的松脱氢工序中，所得的成品中，其它甾体高达4～6％．虽经反复精制也无法降至＜2％。因此产品不能出厂。作者通过高效液相色谱和薄层色谱检测，发现其它甾体不合格的原因是在脱氢转化中产生了一个新的杂质（暂以“X”代表，下同）。为此提出了该杂质产生的原因， I plant the production of prednisone dehydrogenation process, the resulting finished products, other steroids as high as 4 ~ 6%. Although repeated refining can not be reduced to <2%. Therefore, the product can not be shipped. By high performance liquid chromatography and thin-layer chromatography detection, the authors found that the reason for the failure of other steroids is the generation of a new impurity in the dehydrogenation (temporarily “X” representative, the same below). To this end, the reasons for the impurities are raised,