采用免疫花环法对４９例慢性肝炎患者外周血Ｔ淋巴细胞亚群进行观察，发现与正常人相比，慢性肝炎患者Ｔ３＋、Ｔ４＋，Ｔ４＋／Ｔ８＋比值明显低于正常人（Ｐ＜００１），Ｔ８＋明显高于正常人（Ｐ＜００１）；ＣＡＨ－Ｂ、ＣＰＨ－Ｂ的Ｔ３＋、Ｔ４＋、Ｔ４＋／Ｔ８＋比值亦明显低于正常人（Ｐ＜００５），Ｔ８＋明显高于正常人（Ｐ＜００５），而二组间无明显区别（Ｐ＞００５），慢性乙肝（ＣＡＨ－Ｈ、ＣＰＨ－Ｂ）患者的Ｔ淋巴细胞亚群间存在平衡失调，功能紊乱 The immunocyclic method was used to observe the T lymphocyte subsets in peripheral blood of 49 chronic hepatitis patients and found that the ratio of T3 +, T4 +, T4 + / T8 + was significantly lower in patients with chronic hepatitis than in normal people (P <0.01) (P <001). The ratios of T3 +, T4 + and T4 + / T8 + of CAH-B and CPH-B were also significantly lower than those of normal subjects (P <005) (P <005), but there was no significant difference between the two groups (P> 005). There was imbalance and dysfunction of T lymphocyte subsets in patients with chronic hepatitis B (CAH-H, CPH-B)