目的分析并探讨急诊静脉溶栓治疗急性心肌梗死的疗效与临床意义。方法将入我院接受治疗的120例急性心肌梗死患者随机分为两组,其中急诊组60例患者在急诊科实施溶栓操作,对照组60例患者入院后实施溶栓。两组均给予尿激酶150万U,通过静脉滴注30min内完成,对两组间的冠脉再通率、患者病死率以及治疗3周时的心功能等进行比较分析。结果急诊组60例患者的冠脉再通率与心功能均明显好于对照组;两组患者的病死率与并发症无明显差异,两组均未发生死于出血或再灌注心律失常者。溶栓后急诊组60例中有14例(23.3%)出现并发轻度出血,对照组中有16例(26.6%)出现并发轻度出血,但两组均未见重度出血,全部120例患者均未出现有低血压或过敏反应。结论早期静脉溶栓是治疗急性心肌梗死的安全且有效的方法。 Objective To analyze and discuss the efficacy and clinical significance of emergency intravenous thrombolysis in the treatment of acute myocardial infarction. Methods A total of 120 acute myocardial infarction patients admitted to our hospital were randomly divided into two groups. 60 patients in the emergency group were treated with thrombolysis in the emergency department and 60 patients in the control group were thrombolyzed after admission. Both groups were given 1.5 million U of urokinase, which was completed within 30 minutes by intravenous drip. The rate of coronary recanalization, the mortality of patients and the cardiac function at 3 weeks after treatment were compared. Results The emergency department coronary recanalization rate and cardiac function in 60 patients were significantly better than those in control group. There was no significant difference in mortality and complications between the two groups. No death from bleeding or reperfusion arrhythmia occurred in both groups. Twenty-four of the 60 patients (23.3%) in the emergency department after thrombolysis developed mild hemorrhage. In the control group, 16 patients (26.6%) developed mild hemorrhage with no severe bleeding in both groups. All 120 patients No hypotension or anaphylaxis occurred. Conclusion Early intravenous thrombolysis is a safe and effective method for the treatment of acute myocardial infarction.