【摘 要】
：
目的 通过细针穿刺细胞病理学对桥本甲状腺炎(Hashimoto\'s thyroiditis,HT)进行分级,并进一步探讨甲状腺功能、主要血常规参数与细胞学分级之间的相关性.方法 对39名经细胞病理学检查确诊为HT的患者的病理涂片进行回顾性分析,并根据细胞学分级标准进行分级.患者均完成游离甲状腺素(FT4)、游离三碘甲状腺氨酸(FT3)、促甲状腺激素(TSH)、甲状腺球蛋白抗体(TGAb)、甲状腺过氧化物酶抗体(TPOAb)及血常规等检查.结果 大多数患者为桥本甲状腺炎1级(56.4％),其次是2级(
【机 构】
：
东南大学医学院附属南京同仁医院 普外科,江苏 南京 211102;南京市中医院 病理科,江苏 南京 210000;南京市中医院 甲乳外科,江苏 南京 210000
论文部分内容阅读
目的 通过细针穿刺细胞病理学对桥本甲状腺炎(Hashimoto\'s thyroiditis,HT)进行分级,并进一步探讨甲状腺功能、主要血常规参数与细胞学分级之间的相关性.方法 对39名经细胞病理学检查确诊为HT的患者的病理涂片进行回顾性分析,并根据细胞学分级标准进行分级.患者均完成游离甲状腺素(FT4)、游离三碘甲状腺氨酸(FT3)、促甲状腺激素(TSH)、甲状腺球蛋白抗体(TGAb)、甲状腺过氧化物酶抗体(TPOAb)及血常规等检查.结果 大多数患者为桥本甲状腺炎1级(56.4％),其次是2级(28.2％)和3级(15.4％).甲状腺刺激激素水平升高者占46.2％,甲状腺功能减退者占53.8％,甲状腺功能正常者占46.2％.35.9％的患者平均血红蛋白均降低,甲状腺功能减退患者中尤为明显.其他血常规参数,与HT细胞学分级和甲状腺激素水平间无显著相关性(P>0.05).结论 细针穿刺细胞病理学是HT诊断的金标准,细胞学分级可进一步客观反映HT的程度.细胞学分级不能反映甲状腺功能的状态.该研究还发现,大多数甲状腺功能减退患者的血红蛋白水平较低,由此可见甲状腺激素水平的变化对Hb的代谢有一定影响.
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