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目的观察无创正压通气联用排痰机治疗慢性阻塞性肺病急性加重期(AECOPD)并发Ⅱ型呼吸衰竭的临床效果。方法 AECOPD并Ⅱ型呼吸衰竭患者45例,随机分成两组,对照组采用常规治疗+无创正压通气,治疗组在此基础上加用排痰机治疗,观察治疗效果、住院时间及无创呼吸机脱机时间的差异。结果治疗组好转率为86.4%(19/22),对照组73.9%(17/23);治疗组平均达到治疗好转的住院时间为(15.8±4.25)d,对照组为(20.6±3.61)d。两组比较差异有统计学意义(P<0.05),治疗组无创呼吸机脱机时间较对照组明显缩短(P<0.05)。结论无创正压通气联合排痰机治疗AECOPD并呼吸衰竭临床疗效确切安全。
Objective To observe the clinical effect of noninvasive positive pressure ventilation combined with sputum aspirator in treating acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with type Ⅱ respiratory failure. Methods AECOPD and type Ⅱ respiratory failure in 45 patients were randomly divided into two groups, the control group using conventional therapy plus noninvasive positive pressure ventilation, the treatment group on this basis with the use of phlegm machine treatment, observation of treatment, hospital stay and noninvasive ventilator Differences in offline time. Results The improvement rate was 86.4% (19/22) in the treatment group and 73.9% (17/23) in the control group. The average hospitalization time was (15.8 ± 4.25) days in the treatment group and (20.6 ± 3.61) days in the control group . The differences between the two groups were statistically significant (P <0.05). The time of offline treatment of non-invasive ventilator in treatment group was significantly shorter than that in control group (P <0.05). Conclusions Noninvasive positive pressure ventilation combined with sputum aspirator treatment of AECOPD and respiratory failure, the exact effect of clinical efficacy.