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呋喃嘧酮(Furapyrimidone,代号 M-170)化学名为:1-〔(5-硝基-呋喃-2-)甲叉胺基〕-四氢嘧啶-2-酮〔Tetrahydro-1-〔(5-nitro-furfurylidene)-amino〕-2(1H)-pyrimidone〕。是一个有希望的治疗丝虫病新药。药理试验表明,对棉鼠体内的棉鼠丝虫成虫和微丝蚴及长爪沙鼠体内的马来丝虫成虫、血液和腹腔内的微丝蚴均有明显的杀灭作用,其中对棉鼠丝虫成虫作用尤为显著。
Furapyrimidone (code M-170) is known by the chemical name: 1 - [(5-Nitro-furan-2-) methylenimino] -tetrahydropyrimidin-2- -nitro-furfurylidene) -amino] -2 (1H) -pyrimidone]. It is a promising new drug for the treatment of filariasis. Pharmacological tests showed that cotton fiber in vivo adult mice and microfilaria microfilariae and Merionesia molitrix adults, blood and peritoneal microfilaria have significant killing effect, in which the cotton The role of mouse filariasis adult is particularly significant.