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目的:通过描述增强CTC评价结直肠癌临床分期T、N分期的准确性,并与病理分期对照,明确其临床应用价值。方法:本研究共入选诊断为非转移性结直肠癌的病人40例,肠道准备后进行增强CTC扫描,管电压120kV,管电流300mA。评价临床分期并与病理分期对照,分别计算T、N分期符合率并进行一致性检验,以P<0.05认为差异具有统计学意义。结果:临床分期T分期符合率77.5%,一致性较好(k=0.665,P=0.000),N分期符合率82.5%,一致性好(k=0.734,P=0.000),总符合率67.5%。结论:增强CTC可以有效地应用于结直肠癌术前评估,尤其是准确的临床分期,具有指导制定治疗方案、评估预后的重要临床价值。
Objective: To clarify the clinical value of CTC in assessing the clinical stage of T and N staging of colorectal cancer by comparing with pathological staging. METHODS: Forty patients with non-metastatic colorectal cancer were enrolled in this study. After the intestine was prepared, an enhanced CTC scan was performed with a tube voltage of 120 kV and a tube current of 300 mA. The clinical staging was evaluated and compared with the pathological staging. The coincidence rates of T, N staging were calculated and tested for consistency. P <0.05 was considered as statistically significant. Results: The coincidence rate of clinical staging T stage was 77.5%, the consistency was good (k = 0.665, P = 0.000), and the coincidence rate of N stage was 82.5% (k = 0.734, P = 0.000) . Conclusion: CTC enhancement can be effectively applied to the preoperative assessment of colorectal cancer, especially the accurate clinical staging. It has the important clinical value of guiding the development of the treatment plan and evaluating the prognosis.