近年来阐明某些内分泌与代谢疾病的发病原理的注意力集中于靶细胞。当激素(H)到达靶细胞,即与称为受体(R)的特殊蛋白质分子相结合。激素受体复合物(HR)通过一系列变化,最终导致细胞的生物学反应。 H+RHR→细胞效应每种激素的特异性受体数目有限,故能被饱和。激素与受体的结合是可逆的,HR复 In recent years, elucidation of the pathogenesis of certain endocrine and metabolic diseases focus on target cells. When the hormone (H) reaches the target cell, it binds to a specific protein molecule called receptor (R). Hormone receptor complex (HR) through a series of changes, eventually leading to the biological response of cells. H + RHR → Cellular Effects Each hormone has a limited number of specific receptors and is therefore saturated. Hormone and receptor binding is reversible, HR complex