论文部分内容阅读
目的观察激光光凝术对不同分期糖尿病视网膜病变(DR)的控制效果。方法对中、重度非增殖期糖尿病视网膜病变(NPDR)95例(143眼)和增殖期糖尿病视网膜病变(PDR)51例(88眼)行532 nm激光全视网膜光凝(PRP)治疗,术后进行视力和眼底随访12个月。结果 (1)光凝治疗12个月后NPDR组视力提高、不变和下降者分别为14眼(9.79%)、125眼(87.41%)和4眼(2.80%),PDR组分别为3眼(3.41%)、73眼(82.96%)和12眼(13.64)%,差异有统计学意义(Z=-3.353,P=0.001)。(2)眼底荧光素血管造影(FFA)显示,NPDR组眼底改善、稳定和恶化分别为17眼(11.89%)、120眼(83.92%)和6眼(4.20%),而PDR组分别为4眼(4.55%)、76眼(86.36%)和8眼(9.09%),差异有统计学意义(Z=-2.323,P=0.020)。结论激光光凝术对不同级别DR者的治疗效果存在差异,中、重度NPDR患者较PDR患者能够从光凝治疗中获得更为稳定的视力和眼底改善效果。
Objective To observe the control effect of laser photocoagulation on diabetic retinopathy (DR) with different stages. Methods Ninety-five patients (143 eyes) with moderate and severe nonproliferative diabetic retinopathy (NPD) and 51 eyes (81 eyes) with proliferative diabetic retinopathy (PDR) underwent 532 nm laser panretinal photocoagulation (PRP) Visual acuity and fundus follow-up 12 months. Results (1) After 12 months of photocoagulation, the visual acuity, invariability and descent in NPDR group were 14 eyes (9.79%), 125 eyes (87.41%) and 4 eyes (2.80% (3.41%), 73 eyes (82.96%) and 12 eyes (13.64%), the difference was statistically significant (Z = -3.353, P = 0.001). (2) Fundus fluorescein angiography (FFA) showed that the fundus of the NPDR group was improved, stabilized and worsened by 17 eyes (11.89%), 120 eyes (83.92%) and 6 eyes (4.20% (4.55%), 76 eyes (86.36%) and 8 eyes (9.09%), the difference was statistically significant (Z = -2.323, P = 0.020). Conclusions Laser photocoagulation has different therapeutic effects on patients with different grades of DR. Patients with moderate and severe NPDR can obtain more stable vision and fundus improvement from photocoagulation than PDR patients.