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目的研究利巴韦林和地塞米松在贝尔麻痹治疗中的应用效果。方法选取2002年8月至2010年10月中山大学附属第五医院神经内科和口腔科收治的贝尔麻痹患者60例,按就诊顺序随机分为A、B两组,每组30例。A组给予利巴韦林和地塞米松联合治疗,B组仅给予地塞米松治疗。两组患者治疗前、后均以Portmann简易评分法评分,并进行比较分析。结果治疗前,60例患者疗效评分均<9分。治疗后,A组满意率为80.33%,明显高于B组(60.00%),且差异有统计学意义(P<0.05)。结论应用利巴韦林联合地塞米松治疗贝尔麻痹效果良好,值得临床推广。
Objective To study the effect of ribavirin and dexamethasone in the treatment of Bell’s palsy. Methods Sixty patients with Bell’s palsy who were admitted to Department of Neurology and Stomatology, the Fifth Affiliated Hospital of Sun Yat-sen University from August 2002 to October 2010 were randomly divided into A and B groups according to the order of treatment, 30 in each group. Group A received ribavirin and dexamethasone combination therapy, and group B received dexamethasone only. Two groups of patients before and after treatment were rated Portmann simple scoring method, and comparative analysis. Results Before treatment, the efficacy of 60 patients were scored <9 points. After treatment, the satisfaction rate of group A was 80.33%, which was significantly higher than that of group B (60.00%), and the difference was statistically significant (P <0.05). Conclusion The application of ribavirin combined with dexamethasone in the treatment of Bell’s paralysis is effective and worthy of clinical promotion.