OSA是在睡眠过程中反复发生上呼吸道阻塞并导致显著低氧血症和心血管疾病的一种综合征，发生阻塞主要部位是软腭。近来发现OSA患者软腭中存在以间质水肿、单核细胞浸润为特征的炎症，然而炎症与上呼吸道阻塞的关系尚不清楚。NEP是一种广泛存在于呼吸道、肠道和其他器官上皮细胞 OSA is a syndrome that recurrent upper airway obstruction during sleep and causes significant hypoxemia and cardiovascular disease. The main site of occlusion is the soft palate. Recently found in the soft palate of OSA patients with interstitial edema, monocyte infiltration characterized by inflammation, however, the relationship between inflammation and upper airway obstruction is unclear. NEP is a widespread epithelial cells in the respiratory, intestinal and other organs