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目的:比较电视辅助胸腔镜手术(VATS)及传统开胸手术(TOS)治疗早期非小细胞肺癌的临床疗效。方法:收集2006年1月-2009年6月期间行VATS治疗非小细胞肺癌患者28例(VATS组)及同期行TOS治疗非小细胞肺癌患者25例(TOS组),比较两组在手术时间、术中出血量、术后疼痛及胸管引流时间、住院时间、1年后复发、转移、死亡率的差异。结果:VATS组手术时间、胸管引流时间及引流量较TOS组无明显差异(P>0.05);与TOS组相比,VATS组术后疼痛明显减轻、围手术期出血量明显减少,术后住院时间明显低于TOS组(P<0.05)。术后1年两组间复发转移率及死亡率无差异(P>0.05)。结论:全胸腔镜下肺叶切除具有创伤小疼痛小、术后恢复快等优点,是治疗早期非小细胞肺癌较好的方法。
Objective: To compare the clinical efficacy of VATS and TOS in the treatment of early non-small cell lung cancer. Methods: Twenty-eight patients (VATS group) undergoing VATS for treatment of non-small cell lung cancer and 25 patients (TOS group) receiving TOS treatment during the same period from January 2006 to June 2009 were enrolled in this study. , Intraoperative blood loss, postoperative pain and chest tube drainage time, hospital stay, recurrence after 1 year, metastasis, mortality differences. Results: Compared with TOS group, the VATS group had less postoperative pain and less perioperative bleeding than the TOS group (P> 0.05) The length of hospital stay was significantly lower than that of TOS group (P <0.05). There was no difference in recurrence, metastasis and mortality between the two groups after 1 year (P> 0.05). Conclusion: Thoracoscopic lobectomy has the advantages of small trauma and rapid recovery after operation, which is a good method for the treatment of early stage non-small cell lung cancer.