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甾类药物系指甾类激素及其类似物,主要包括性激素和肾上腺皮质激素及其衍生物,它们具有较强的生理活性,是临床常用的一类药物。从甾类药物的化学结构入手,探讨甾类药物的性质、反应和活性是研究甾类药物的基本方法。因此,有必要了解和掌握甾类药物的构造、构型和构象。甾类药物的构造甾类药物的基本构造为环戊烷并多氢菲,一般C_(10)和C_(13)各有一个甲基,称为角甲基;C_(17)常有一个含氧的功能基或一个碳
Steroid drugs are steroid hormones and their analogs, including sex hormones and adrenal hormones and their derivatives, they have strong physiological activity, is a commonly used class of drugs. Starting from the chemical structure of steroids, to explore the nature of steroids, reactions and activity is the basic method for the study of steroids. Therefore, it is necessary to understand and master the structure, configuration and conformation of steroids. The basic structure of steroid drugs is cyclopentane and hydrogen-rich phenanthrene, the general C_ (10) and C_ (13) each have a methyl group, known as angle methyl; C_ (17) often contains a Oxygen functional group or a carbon